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💊Pharmacology·15 min·Sample Lesson

Antibiotics — Use and Misuse

ANTIBIOTICS are medicines that KILL or STOP bacterial infections. Their discovery (penicillin, 1928, Alexander Fleming) revolutionized medicine. Before antibiotics, infections from minor cuts could kill. Childbirth, surgery, even simple ear infections were often fatal. Today, antibiotics make routine medicine possible. But MISUSE is creating ANTIBIOTIC RESISTANCE — bacteria evolving to survive treatment. The WHO calls it one of the top global health threats.

Common antibiotics. PENICILLINS, CEPHALOSPORINS: kill bacteria by disrupting cell wall construction. TETRACYCLINES, MACROLIDES: stop bacterial protein synthesis. FLUOROQUINOLONES: target bacterial DNA replication. Each works differently. Different drugs work on different bacteria. Some antibiotics are NARROW SPECTRUM (target specific bacteria); others BROAD SPECTRUM (kill many types — but also disrupt good bacteria more).

You have a COLD (caused by viruses). Will antibiotics help?

How to use antibiotics responsibly. (1) ONLY when prescribed for confirmed bacterial infection. (2) FINISH the entire course (stopping early lets resistant bacteria survive). (3) Never share antibiotics. (4) Don't pressure doctors for antibiotics for viral infections. (5) Prevent infections (hand washing, vaccines) — best way to reduce antibiotic need. Globally, the heaviest antibiotic users are AGRICULTURAL — cattle, poultry use vastly more antibiotics than humans, driving resistance. Reform is needed across systems.

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Be a Steward

When was the last time you (or a family member) took antibiotics? Was it truly needed? Knowing the right answer can reduce unnecessary use globally. Ask doctors: "Is this really bacterial?" That's smart healthcare.

Antibiotics are one of the great gifts of modern medicine. Resistance threatens to take them away. Each prescription is a tiny bit of a global resource — using them wisely is a public health duty.

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